Levomefolate calcium 635 views0 applications

Australian approved name (AAN): Levomefolate calcium

Common names and synonyms:
Levomefolate calcium anhydrous
Levomefolinate calcium
Calcium L-5-methyltetrahydrofolate
Vitamin B9

Molecular formula: C20H23CaN7O6

Molecular weight: 497.52

Conversion (% Levomefolic acid): 92.35

RDI for Vitamin B9 as per NHMRC:
Infants 0-6 months 65µg/day (as folate) (AI)
Infants 7-12 months 80µg/day
Children – 1-3 years – 150µg/day (AI)
Children – 4-8 years – 200µg/day (AI)
Children – 9-13 years – 300µg/day
Children – 14–18 years – 400µg/day
Adults – 400µg/day
Pregnancy – 600µg/day
Lactation – 500µg/day

Maximum daily dose: 500µg. The maximum recommended daily dose must provide no more than 500 micrograms of Levomefolic acid from Levomefolate calcium. When folic acid, folinic acid, levomefolate salts and/or their derivatives are used in combination, the medicine must provide no more than a total of 500 micrograms of folic acid, folinic acid, levomefolate salts and/or their derivatives in total per maximum recommended daily dose.

Mandatory component: Levomefolic acid

Warnings and restrictions:  Only for use in oral medicines.

VIT – Vitamins can only be of assistance if the dietary vitamin intake is inadequate. OR Vitamin supplements should not replace a balanced diet.

When used in preparations indicated for reducing the risk of having a child with spina bifida/neural tube defects:
a) the maximum daily dose must provide 400 – 500 micrograms of folic acid; and
b) the following statements must be included on the label:
NEUR – Warning: Do not exceed the stated dose except on medical advice. If you have had a baby with a neural tube defect/spina bifida – seek specific medical advice (or words to that effect).

Alllowable purpose of the ingredient: Active

TGA reference: Merck Index

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